Suz12 binds to silenced regions of the genomein a cell-type-specific manner
نویسندگان
چکیده
منابع مشابه
Suz12 binds to silenced regions of the genome in a cell-type-specific manner.
Suz12 is a component of the Polycomb group complexes 2, 3, and 4 (PRC 2/3/4). These complexes are critical for proper embryonic development, but very few target genes have been identified in either mouse or human cells. Using a variety of ChIP-chip approaches, we have identified a large set of Suz12 target genes in five different human and mouse cell lines. Interestingly, we found that Suz12 ta...
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ژورنال
عنوان ژورنال: Genome Research
سال: 2006
ISSN: 1088-9051
DOI: 10.1101/gr.5306606